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Aspirin reverses cancer risk in the obese: Study

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London: A regular dose of aspirin reduces the long-term risk of cancer in overweight people with a family history of the disease, new research has found.

The study found that being overweight more than doubles the risk of bowel cancer in people with Lynch Syndrome, an inherited genetic disorder which affects genes responsible for detecting and repairing damage in the DNA.

Around half of these people develop cancer, mainly in the bowel and womb.

However, over the course of a ten year study the researchers found this risk could be counteracted by taking a regular dose of aspirin.

“This is important for people with Lynch Syndrome but affects the rest of us too. Lots of people struggle with their weight and this suggests the extra cancer risk can be cancelled by taking an aspirin,” said one of the researchers John Burn, professor of clinical genetics at Newcastle University in England.

“This research adds to the growing body of evidence which links an increased inflammatory process to an increased risk of cancer,” Burn noted.

“Obesity increases the inflammatory response. One explanation for our findings is that the aspirin may be suppressing that inflammation which opens up new avenues of research into the cause of cancer,” he explained.

The international study involving scientists and clinicians from 16 countries followed nearly 1,000 patients with Lynch Syndrome, in some cases for over 10 years.

The patients began either taking two aspirins (600 mg) every day for two years or a placebo.

When they were followed up ten years later, 55 had developed bowel cancers and those who were obese were more than twice as likely to develop this cancer – in fact 2.75 times as likely.

“Our study suggests that the daily aspirin dose of 600 mg per day removed the majority of the increased risk associated with higher BMI (body mass index),” professor Tim Bishop from the University of Leeds who led on the statistics for the study noted.

However, the researchers noted that before anyone begins to take aspirin on a regular basis they should consult their doctor as aspirin is known to bring with it a risk of stomach complaints including ulcers.

The study was published today in the Journal of Clinical Oncology.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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