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Steep weight loss in older women indicates Alzheimer’s risk

Published

9 years ago

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London: Women with a gene variant associated with Alzheimer’s disease experience a steeper decline in body mass index (BMI) after age 70 than those women without the version of the gene, says a study.

The finding adds to a body of evidence suggesting that body weight change may aid in the diagnosis and management of Alzheimer’s disease.

“In this study, we followed Swedish women for almost 40 years from mid-life ages of 38-60 years,” said lead researcher Deborah Gustafson from University of Gothenburg in Sweden.

“We tracked their BMI in relation to dementia onset, and considered the potential role of the APOEe4 allele, a known risk factor for late-onset dementia,” she explained.

“We show that those with the APOEe4 allele experience greater or steeper decline in BMI after age 70 years, whether they develop dementia or not,” Gustafson noted.

The results suggest that body weight change and BMI are easily measured, non-invasive potential indicators for dementia management.

“Better understanding of a relatively common risk allele such as APOEe4 and how it modifies risk may aid in our understanding of how we can better intervene among those at highest risk for dementia,” Gustafson said.

The study was published online in the Journal of Alzheimer’s Disease.

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Corona

Covid toll in Karnataka is a worrying sign for state government

Published

3 years ago

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May 4, 2022

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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