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Blood test could determine preeclampsia disorder risk

Published

9 years ago

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London: A new blood test could reveal the early start of preeclampsia, a multi-system disorder that affects women in pregnancy, the researchers said.

The test which determines the ratio of sFlt-1 to PlGF — two placental proteins — can be used to predict whether a pregnant woman will develop preeclampsia or the typical complications associated with it, the researchers said.

The researchers were able to determine a cutoff value for the ratio of serum sFlt-1 to PlGF, which allows them to reliably rule out the condition within one week.

“The ratio of serum sFlt-1 to PlGF can help us to better predict the risk of disease onset or its progression,” emphasised the study’s corresponding author Stefan Verlohren from Charite – University Medicine Berlin, Germany.

The findings of the new study may help in avoiding preterm deliveries and delays in starting the treatment of preeclampsia.

Preeclampsia affects two to five percent of pregnant women, and is one of the main reasons for complications during the second half of pregnancy. It is most often diagnosed too late and in some severe cases can turn fatal for both mother and the child.

A total of 1,273 pregnant women with suspected preeclampsia, recruited from 14 different countries, took part in the study.

All participants underwent blood tests to determine the ratio of serum sFlt-1 to PlGF. A sFlt-1 to PlGF ratio of 38 or lower was shown to have a negative predictive value of close to 100 percent for ruling out preeclampsia within one week.

The findings were detailed in the New England Journal of Medicine.

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Corona

Covid toll in Karnataka is a worrying sign for state government

Published

3 years ago

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May 4, 2022

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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