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Researchers develop process to destroy brain tumours

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New York: A new study has lately developed a process by which skin cells can turn into cancer-hunting stem cells that can raze brain tumours known as glioblastoma.

The discovery can offer, for the first time in more than 30 years, a new and more effective treatment for the disease, the study said.

“Patients desperately need a better standard of care,” said Shawn Hingtgen, assistant professor at the University of North Carolina at Chapel Hill in the US.

The survival rate beyond two years for a patient with glioblastoma is 30 percent because it is so difficult to treat.

Even if a surgeon removes most of the tumour, it is nearly impossible to get the invasive, cancerous tendrils that spread deeper into the brain and inevitably the remnants grow back.

The new technique, reported in the journal Nature Communications, builds upon the newest version of the Nobel Prize-winning technology from 2007, which allowed researchers to turn skin cells into embryonic-like stem cells.

In their work, the research team reprogrammed skin cells known as fibroblasts – which produce collagen and connective tissue — to become induced neural stem cells.

Working with mice, Hingtgen’s team showed that these neural stem cells have an innate ability to move throughout the brain and home in on and kill any remaining cancer cells.

The team also showed that these stem cells could be engineered to produce a tumour-killing protein, adding another blow to the cancer.

Depending on the type of tumour, Hingtgen’s team increased survival time of the mice from 160 to 220 percent.

The next steps will focus on human stem cells and testing more effective anti-cancer drugs that can be loaded into the tumour-seeking neural stem cells.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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