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Exercise hormone can help shed, prevent fat

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Exercise hormone can help shed, prevent fatNew York : Does working out feels like more of pain to you? Take heart. Exercise releases a hormone that can help your body shed fat and keep it from forming again, which may also act as potential target to fight obesity, diabetes and other health issues, a study has found.

The results showed that hormone irisin helps convert calorie-storing white fat cells into brown fat cells that burn energy and may be an attractive target for fighting obesity and diabetes.

“Exercise produces more irisin, which has many beneficial effects including fat reduction, stronger bones and better cardiovascular health,” said Li-Jun Yang, Professor at the University of Florida.

The hormone works by boosting the activity of genes and UCP1 — a protein crucial to turning white fat cells into brown cells.

Further, irisin, which surges when the heart and other muscles are exerted, also inhibits the formation of fatty tissue.

For the study, researchers collected fat cells donated by 28 patients who had breast reduction surgery.

After exposing the samples to irisin, they found a nearly five-fold increase in cells with protein UCP1 — crucial to fat “burning”.

“We used human fat tissue cultures to prove that irisin has a positive effect by turning white fat into brown fat and that it increases the body’s fat-burning ability,” Yang said.

Moreover, among the tested fat-tissue samples, the team found that irisin also reduced the number of mature fat cells by 20 to 60 per cent compared with those of a control group.

That suggests irisin reduces fat storage in the body by hindering the process that turns undifferentiated stem cells into fat cells while also promoting the stem cells’ differentiation into bone-forming cells, the researchers said.

The findings about irisin’s role in regulating fat cells sheds more light on how working out helps people stay slender, Yang said.

The study was published recently in the American Journal of Physiology — Endocrinology and Metabolism.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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