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How lung cancer can be stopped from spreading

Published

10 years ago

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London: To break loose and spread around the body, lung cancer cells first chop of the protein ties that bind them to other cells, new research shows, adding that targeting this flaw could help stop lung cancer from spreading.

“This research shows for the first time how lung cancer cells sever ties with their neighbours and start to spread around the body, by hijacking the cells’ recycling process and sending it into overdrive,” said lead researcher Angeliki Malliri from Cancer Research UK Manchester Institute at University of Manchester.

Ties which bind cells together – controlled by a protein called TIAM1 – are chopped up when cell maintenance work goes wrong, the findings showed.

Healthy cells routinely scrap old cell parts so they can be broken down and used again. But this process spirals out of control in lung cancer cells, which scrap too many TIAM1 ties.

Targeting this recycling process could stop lung cancer from spreading by keeping the cells stuck firmly together.

“Early-stage research like this is essential to find treatments which could one day block cancer spread – which would be a game changer,” Nell Barrie from Cancer Research UK said.

The study was published in the journal Cell Reports.

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Corona

Covid toll in Karnataka is a worrying sign for state government

Published

3 years ago

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May 4, 2022

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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