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Diabetes may be detected 20 years before diagnosis says study

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Early signs of Type-2 diabetes can be detected 20 years before diagnosis, according to a new research.

Researchers from Aizawa Hospital in Japan found that increased fasting glucose, higher body mass index (BMI) and impaired insulin sensitivity were detectable 10 years before the diagnosis of diabetes as well as prediabetes.

As the vast majority of people with Type-2 diabetes go through the stage of prediabetes, our findings suggest that elevated metabolic markers for diabetes are detectable more than 20 years before its diagnosis, said Hiroyuki Sagesaka, lead researcher from the varsity.
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According to present studies, diabetes can be detected 20 years before its diagnosis unlike the previous research which suggested that risk factors like obesity and elevated fasting glucose may be present up to 10 years before someone is diagnosed with the issue.

In the beginning of the study, 27,392 non-diabetic individuals had a fasting glucose and average blood glucose (HbA1c) measured and were followed until a diagnosis of Type-2 diabetes or prediabetes.

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Over the study period, 1,067 new Type-2 diabetes cases were identified. Of the 15,778 individuals with normal blood glucose at the initial health exam, 4,781 developed prediabetes and the same abnormalities, although to a milder degree, that were present at least 10 years before diagnosis of prediabetes, the findings revealed.

Because trials of prevention in people with prediabetes seem to be less successful over long-term follow up, we may need to intervene much earlier than the prediabetes stage to prevent progression to full blown diabetes, Sagesaka said.

The research has important implications given that an estimated 425 million adults (aged 20-79 years) were living with diabetes in 2017, and this is predicted to rise to 629 million by 2045.

The study was presented at European Association for the Study of Diabetes (EASD) Annual Meeting in Berlin in Germany.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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