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Common cold in past may give protection from Covid-19
In a big breakthrough, researchers have found that people who have had a bout of seasonal or common cold in the past may get protection from Covid-19. The study, published in the journal mBio, also suggests that immunity to Covid-19 is likely to last a long time — maybe even a lifetime.
The study showed that the Covid-19-causing virus, SARS-CoV-2, induces memory B cells, long-lived immune cells that detect pathogens, create antibodies to destroy them and remember them for the future.
The next time that pathogen tries to enter the body, those memory B cells can hop into action even faster to clear the infection before it starts.
Because memory B cells can survive for decades, they could protect Covid-19 survivors from subsequent infections for a long time, but further research will have to bear that out, the researchers said.
The study is also the first to report cross-reactivity of memory B cells — meaning B cells that once attacked cold-causing coronaviruses appeared to also recognise SARS-CoV-2.
Study authors believe this could mean that anyone who has been infected by a common coronavirus — which is nearly everyone — may have some degree of pre-existing immunity to Covid-19.
“When we looked at blood samples from people who were recovering from Covid-19, it looked like many of them had a pre-existing pool of memory B cells that could recognise SARS-CoV-2 and rapidly produce antibodies that could attack it,” said lead study author Mark Sangster from the University of Rochester in the US.
The findings are based on a comparison of blood samples from 26 people who were recovering from mild to moderate Covid-19 and 21 healthy donors whose samples were collected six to 10 years ago — long before they could have been exposed to Covid-19.
From those samples, study authors measured levels of memory B cells and antibodies that target specific parts of the Spike protein, which exists in all coronaviruses and is crucial for helping the viruses infect cells.
The Spike protein looks and acts a little different in each coronavirus, but one of its components, the S2 subunit, stays pretty much the same across all of the viruses.
Memory B cells can’t tell the difference between the Spike S2 subunits of the different coronaviruses and attack indiscriminately.
The study found that was true for beta coronaviruses, a subclass that includes two cold-causing viruses as well as SARS, MERS and SARS-CoV-2.
“Now we need to see if having this pool of pre-existing memory B cells correlates with milder symptoms and shorter disease course — or if it helps boost the effectiveness of Covid-19 vaccines,” the authors wrote.
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Dr. Abhishek Verma Dedicates a Shelter in Memory of His Mother, Veena Verma, at KGMU; Inaugurated by Daughter Nicolle Verma
World-renowned business tycoon Dr. Abhishek Verma has supported Foodman Vishal Singh’s Hunger-Free World mission. In memory of his mother, Late Veena Verma, who was a 3 term Rajya Sabha MP.
Dr. Verma dedicated a state-of-the-art free permanent shelter for the attendants of patients at KGMU Medical University, Lucknow, under the aegis of Vijay Shree Foundation. His daughter, Nicolle Verma, inaugurated the shelter.
During the event, Foodman Vishal Singh honored Nicolle Verma by presenting her with a memento. Mrs. Nidhi Sharma and Avantika Yadav, associated with the organization, welcomed her with garlands. Following this, Nicolle Verma distributed essential items to the attendants and also handed out fruits. She became emotional remembering her grandmother on her birth anniversary.
On this occasion, she also inaugurated the “Veena Verma Sevalaya” in memory of her grandmother, Veena Verma, to serve the attendants. She expressed, “I feel proud that my family is engaged in nation-building as well as social service. Today, in collaboration with Vijay Shree Foundation founder Foodman Vishal Singh Ji, I feel immensely proud to dedicate this shelter for the poor, helpless, and needy attendants of patients battling serious illnesses like cancer. I am honored to be associated with the Hunger-Free World Mission for humanity.”
Inspired by the continuous humanitarian service provided by Vijay Shree Foundation over the past 17 years, Nicolle Verma donated 10 lakh rupees to support the cause. The purpose of this donation is to ensure that services continue for the needy attendants of patients suffering from severe illnesses in hospitals, as facilitated by Foodman Vishal Singh.
It is noteworthy that Dr. Abhishek Verma’s family has a legacy of public and philanthropic service. They are helping millions to carry forward the values and service work of their parents. On the occasion of his mother’s birth anniversary, Dr. Abhishek Verma dedicated this state-of-the-art permanent shelter at Lucknow Medical College to serve the attendants of patients through the Vijay Shree Foundation.
Supporting Foodman Vishal Singh’s Hunger-Free World mission, Dr. Abhishek Verma assured that he would continually support keeping this flame of humanity alive. He also promised to assist in providing medicines to the helpless patients.
Continuing her grandmother’s legacy of service, Nicolle Verma personally served food to the needy patients and attendants. She said, “It is our good fortune to have received the joy of doing this noble work today through Foodman Vishal Singh. I have taken another step forward in carrying my family’s values and cooperation by joining hands with the Vijay Shree Foundation. My father taught me to serve and help the needy, and I feel happy when I bring a smile to someone’s face.”
On the birth anniversary of the late Veena Verma, the event organizer, Vijay Shree Foundation founder Foodman Vishal Singh, said, “We feel proud and happy that Dr. Abhishek Verma, a globally renowned business tycoon, has extended his support to uplift our country from the hunger index. Today, on his mother’s birth anniversary, he inaugurated a state-of-the-art permanent shelter at Lucknow Medical College, which will always be helpful for the needy attendants of patients. It is a pleasure for me and the organization to receive the affection of Mr. Verma.”
The event was attended by General Manager Verma Family Office Hemant Garg, Sonu Rajput, and the organization’s volunteers, including Sandeep Singh, Parmeshwar Ji, Prashant Rao Gautam, Balram Singh, Ramesh Chaudhary, Suman, Jeetu, Anil, Suraj, Vinay, Manish Bhadauria, Manas Mehrotra, Vivek, Apurv, Happy, and others.