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DNA repair method prevents disease

Published

9 years ago

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Moscow: A team of Russian researchers has discovered a mechanism of DNA repair that will help prevent and treat diseases in the future.

The DNA molecule is chemically unstable, giving rise to DNA lesions of different nature.

That is why DNA damage detection, signalling and repair are needed.

The damage of the DNA, if not repaired, leads to accumulation of mutations, cell death and to the development of various diseases, including Alzheimer’s.

“We have shown, not yet in the cell but in vitro, that the repair of breaks in the other DNA chain, which is “hidden” in the nucleosome, is still possible,” said Vasily M Studitsky, professor at Lomonosov Moscow State University.

In higher organisms, DNA is bound with proteins in complexes called the nucleosome.

The mechanism of DNA repair opens up new perspectives for the treatment and prevention of neurodegenerative diseases.

The article was published in the journal Science Advances.

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Corona

Covid toll in Karnataka is a worrying sign for state government

Published

3 years ago

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May 4, 2022

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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